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Aβ1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aβ 1 42  (Elabscience Biotechnology)
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical <t>Aβ</t> <t>1–42</t> , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention
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Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical Aβ 1–42 , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention

Journal: Molecular Biomedicine

Article Title: Docosahexaenoic acid remodels lipid composition of lipid rafts and mitochondrial function in ApoE4/4 mouse brain: a multi-omic investigation

doi: 10.1186/s43556-026-00618-x

Figure Lengend Snippet: Growth, Behavioral Performance, and Cortical AD-Related Marker Levels in Mice. a Schematic overview of the experimental design. b - c Changes in body weight ( b ) and dietary intake ( c ) of mice in each group during the intervention period ( N ≥ 7, mean ± SEM). d - e Morris water maze performance: acquisition phase ( d ) and probe trial ( e ) ( N ≥ 7, mean ± SEM). f Cortical ApoE levels (pg/mg protein) ( N = 4). g : Cortical Aβ 1–42 , Aβ 1–40 and Aβ 1–40/Aβ1–42 ratios (pg/mg protein) ( N = 4). h – l Cortical expression of proteins related to Aβ synthesis and degradation ( h ), tau protein and phosphorylated tau( j - l ) ( N ≥ 3). ApoE, apolipoprotein E; Aβ, amyloid-beta protein; APP, amyloid precursor protein; BACE1, β-site APP cleaving enzyme 1; LRP1, low-density lipoprotein receptor-related protein 1; IDE, insulin-degrading enzyme; TAU, tau protein. Statistical significance: *** P < 0.001, ** P < 0.01, * P < 0.05, ### P < 0.001, ## P < 0.01, # P < 0.05 vs. corresponding group after 6-month intervention

Article Snippet: The levels of ApoE (RK00231, ABclonal, China), Aβ 1–40 (E-EL-M3009, Elabscience, China), and Aβ 1–42 (E-EL-M3010, Elabscience, China) were quantified following the instructions.

Techniques: Marker, Expressing, Transmission Electron Microscopy, Polymerase Chain Reaction